When Is The Best Time To Take Zoloft

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A. The best time to take zoloft is within the first few weeks of starting treatment, especially if you are taking it for depression or anxiety. Zoloft can make you drowsy, so avoid driving after taking this medication unless absolutely necessary. Do not stop taking your medication suddenly without checking with your doctor first. Stopping suddenly may cause unpleasant withdrawal symptoms that could interfere with being able to function normally in daily life.