When Is The Best Time To Take Wellbutrin

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Wellbutrin is a biphasic antidepressant. In other words, it works differently depending on the dosage you take and the length of time that you have been taking it. Most patients experience an increase in energy, better sense of well-being, and improved mood within two days after starting treatment with Wellbutrin SR tablets. The initial “kick” or boost to your mood occurs within 24 hours while the antidepressant action becomes apparent after a few weeks of regular use. Patients who continue to take Wellbutrin for at least 4 months see their symptoms improve further.[1]

What does wellbutrin do?

The exact mechanism by which Wellbutrin improves depression is unknown but may be related to its ability to block several different types of receptors in the brain (serotonin, norepinephrine, dopamine). Certain antidepressants such as monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants (TCAs), and selective serotonin reuptake inhibitors (SSRIs) are known to work by affecting specific neurotransmitters above all others; they act only on one type of neuron receptor or transmitter at a time. For example: most MAOIs affect noradrenergic neurons located near areas where they send messages out into the brain; thus these drugs also reduce excessive amounts of certain natural substances called monoamines found in nerve cells.[2] Tricyclic antidepressants like amitriptyline affect both norepinephrine and dopamine neurons,[