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“Fluoxetine has been shown to be effective in the short-term treatment of major depression. In a 4 week, double blind study with fluoxetine versus placebo, there was a significant improvement at endpoint on the Hamilton Depression Rating Scale.” – Source: http://www.drugs.com/pro/fluoxetine.html#1 “Fluoxetine is indicated for… Treatment of Major Depressive Disorder (MDD) in adults and adolescents aged 13 years and older when used concomitantly with other antidepressant drugs.” – Source: http://www.fda.gov/cder/guidancecomplianceregulatoryinformationhealthexaminationenvironmentservicesprovidershealthcarepersonsnursesdoctorspharmacypractitionersandothermedicalprofessionals/#page2 “Major depressive disorder (MDD), known medically as unipolar or clinical depression, causes severe disturbances in mood that adversely affect functioning at home, work or school; it may seriously impair social or occupational life; and cause physical symptoms like insomnia …” – Source: http://psychcentral.com/lib/depression-pathophysiology/#workbook_section_5 “The 5th Edition of the Diagnostic & Statistical Manual of Mental Disorders defines MDD as persistent depressive episodes lasting more than 2 weeks…” – Source: https://www4aapdci