When Is The Best Time To Take Spiriva

?

My boyfriend is on Spiriva and he has to take it once a day. He also takes other medicine that can cause him to stop breathing, so I am wondering how long before his next dose does he need to start taking this? It’s kind of hard for me because the box says one pill at 12 noon but I don’t know if that is morning or afternoon. Could you please help us out? Also thanks so much! -Natalie💛