seroquel is the only medication that has been shown to decrease cognitive impairment in people with dementia. It can be taken at any time, but it’s best to start taking seroquel as early as possible. Some experts recommend starting with one half of a 50 mg tablet once daily and increasing dose if needed after 3-5 days. A total daily dose range from 180mg to 900mg depending on your individual needs! The maximum recommended duration of treatment is 9 months for mild, chronic or severe Alzheimer’s Disease or related dementias. If you are not certain about how much medication will help your loved one, speak first with their primary physician!