I like to wash my clothes at least once a week. When I feel or smell the difference in the fabric, I know it is time for a fresh pair of clothes! However, there are times when you can make your own schedule. It depends on how often you wear them and if they need dry clean only clothing. Also consider that laundry detergents fade color over time so washing with colored fabrics will be more noticeable. My husband loves his black t-shirts but he wears all black shirts every day so he doesn’t mind me washing them frequently without any problems! If you have lots of children then this may not matter as much because their shirts tend to fade quickly anyway due to spills and food coloring stains from snacks!